Botox-Dysport study open

SAN ANTONIO (Sept. 29, 2010) – The brand Botox has been around a while, but it’s getting a fresh test in a new study that volunteers can sign up for, comparing it with another wrinkle treatment at The University of Texas Health Science Center at San Antonio.

The School of Medicine’s division of dermatology and cutaneous surgery is conducting an IRB-approved clinical study comparing Botox with Dysport, another FDA-approved drug used in standard doses for the treatment of forehead wrinkles. In this study, volunteers will receive injections of Botox Cosmetic and Dysport into the forehead to reduce wrinkles. It will compare Botox to Dysport, with one injected on each side of the area between the eyebrows.

Researchers are seeking 100 healthy individuals 18-65 years old who are planning to receive Botox or Dysport but are prepared to wait until February 2011 to receive both in this study. The study will continue to accept patients until it is full.

Participants will receive the injection in February 2011 at the Cancer Therapy & Research Center, in the dermatology clinic on the third floor of the Grossman building. The dermatology physicians are part of the School of Medicine multi-specialty practice called UT Medicine San Antonio.

Patients will also have four scheduled follow-up visits during the six months after injection. The follow-up visits will be for photographs only, except for patients who need a touch-up in the first week. There is some cost to the patient, although injections will be offered at a reduced cost of about $200. The typical cost is approximately $700.

Interested people should call 210-450-9840 to schedule an informational “Botox Study” appointment with principal investigators Bahar F. Firoz, M.D., M.P.H., or Wenhong Zhou, M.D. If you qualify, you will be scheduled for injection in February 2011.

Those who don’t qualify include anyone who is pregnant, breastfeeding or planning pregnancy, anyone planning to receive Botox or Dysport injections from an outside physician within the next six months, and anyone with an allergy to the medication. Other possible conditions that would disqualify a participant will be discussed at the informational appointment.

UT Medicine San Antonio is the clinical practice of the School of Medicine at the UT Health Science Center at San Antonio. With more than 700 doctors – all faculty from the School of Medicine – UT Medicine is the largest medical practice in Central and South Texas, with expertise in more than 60 different branches of medicine. Primary care doctors and specialists see patients in private practice at UT Medicine’s clinical home, the Medical Arts & Research Center (MARC), located in the South Texas Medical Center at 8300 Floyd Curl Drive, San Antonio 78229. Most major health plans are accepted, and there are clinics and physicians at several local and regional hospitals, including CHRISTUS Santa Rosa, University Hospital and Baptist Medical Center. Call (210) 450-9000 to schedule an appointment, or visit the Web site at for a complete listing of clinics and phone numbers. For more information on the many ways “We make lives better®,” visit

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