Molecule shows potential to combat treatment resistance in brain tumor glioblastoma

May 17, 2023

Glioblastoma-impacted mice lived longer when treated with combination of molecule drug and chemotherapy agent Glioblastoma (GBM), a highly devastating brain tumor, has long posed challenges as effective treatments have remained elusive. Despite responding initially to treatment, GBM patients often experience therapy resistance leading to low long-term survival rates, with only 7.2% of patients surviving beyond […]

Flies, worms poorly predict drugs’ life span effects in mice, study indicates

April 21, 2023

Doctoral student’s research suggests difficulty of translating longevity interventions from lower species to mammals If a drug extends the life span of worms or flies, is it likely to do the same in mice? Michael Bene, PhD student Not typically based on the existing data, said Michael Bene, a sixth-year doctoral student at The University […]

Select cells ‘home in on the skin like guided missiles’ at birth to enhance immunity

April 13, 2023

Protection is afforded infants against disease-causing bacteria Certain immune cells possess a homing property that directs them to the skin at birth to protect the baby, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) discovered. “These T cells home in on the skin like a guided missile,” […]

Novel drug makes mice slim even on sugary, fatty diet

March 22, 2023

Compound limits magnesium transport in cellular power plants called mitochondria. Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have developed a small-molecule drug that prevents weight gain and adverse liver changes in mice fed a high-sugar, high-fat Western diet throughout life. “When we give this drug to […]