Power outage: Research offers hint about heart weakness in Barth syndrome

July 1, 2020

Barth syndrome is a rare condition that occurs almost exclusively in males. Symptoms include an enlarged and weakened heart. The condition is present at birth or becomes evident early in life. Life expectancy is shortened and there is no treatment. The laboratory of Madesh Muniswamy, PhD, in the Long School of Medicine, found a clue […]

Heart



When it comes to DNA repair, it’s not one tool fits all

June 26, 2020

Our cells are constantly dividing, and as they do, the DNA molecule – our genetic code – sometimes gets broken. DNA has twin strands, and a break in both is considered especially dangerous. This kind of double-strand break can lead to genome rearrangements that are hallmarks of cancer cells, said James Daley, PhD, of the […]