Sudha Seshadri, M.D., FAAN, director of the Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases, and the Robert R. Barker distinguished university professor of neurology at UT Health in San Antonio, discusses the association between APOE4 and the KLOTHO variant and how it confirms that this KLOTHO variant is protective in people at highest risk for Alzheimer’s.
